Mood Disorder of My Uncle

In my family, I think my uncle has some mood disorders. My uncle is a business man. At first, I think he has mental pressure and his character is sentimental. However, he fusses too much about his business. For this reason, he can't sleep nights. Then he became easily aroused to anger and wrathful by temperament, even lost his hair. It is last several months. I suggested to him that went to see a psychological doctor, but he did not go. Maybe he deny that he have a problem. Now, his business go with a swing, so his problem has a bit of grow better. Indeed, his problem did not disappear because he still sleep very Weill at sometimes.